輝瑞承認曾「將原始新冠病毒用於表達來自新的『受關注的變種』的棘蛋白（spike protein）」（英文：we have conducted research where the original SARS-CoV-2 virus has been used to express the spike protein from new variants of concern），用來研究現存疫苗對變種嘅效用。
原始新冠病毒，表達變種嘅棘蛋白，咪即係整咗變種出來囉。有錯請指正。
更清楚嘅係，輝瑞承認，研發佢嘅新冠藥PAXLOVID時，喺有限情況中製造過變種新冠病毒。(In a limited number of cases when a full virus does not contain any known gain of function mutations, such virus may be engineered to enable the assessment of antiviral activity in cells.)
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